The use of anti-inflammatory ibuprofen drugs
Ibuprofen is a non-steroidal anti-inflammatory drug. (Nonsteroidal Anti-Inflammatory Drugs: NSAIDs) are commonly used to treat pain, fever, and inflammation from various causes such as headache, toothache, backache, arthritis, menstrual pain. And minor injuries
Mechanism of action of Ibuprofen
Ibuprofen has a mechanism of action by helping to inhibit the synthesis of prostaglandins. (Prostaglandins) in the tissues of the body Helps to inhibit the activity of Cyclooxygenase enzymes 1 and 2 (Cyclooxygenase; COX-1 and COX-2), therefore has anti-inflammatory effect. Relieving pain and reducing fever
How to use ibuprofen
- Adults start taking 400 mg of the drug and then take 200-400 mg as needed every 4 hours but no more than 4 times a day.
- Children take every 6 hours but no more than 4 times a day. The dosage of the drug depends on the child's body weight as follows:
- Body weight 7-8 kg, taking a dose of 50 mg
- Body weight 9-10 kilograms, taking 75 mg of the drug
- Body weight 11-16 kilograms, taking 100 mg of the drug
- Body weight 17-21 kilograms, taking 150 mg of the drug
- Body weight 22-27 kilograms, taking 200 mg of the drug.
- Body weight 28-32 kilograms, taking a dose of 250 mg
- Body weight 33-43 kilograms, taking 300 mg of the drug
- Body weight above 44 kilograms Take 400 mg of the drug as an adult.
NSAIDs dosage
NSAIDs, doctors prescribe the drug according to the conditions of each patient, such as 1-4 times a day, may be more or less. Depending on how long the drug will accumulate in the body. Or the age and weight of the patient Doctors may increase the potency of the drug in patients with rheumatoid arthritis. Or reduce the strength of the drug in patients with osteoarthritis or muscle injury Sample doses of NSAIDs
Warnings about the use of NSAIDs
- This drug should not be used in children younger than 6 months.
- This drug should not be used for people with a history of allergic reactions to NSAIDs, especially if having a severe allergic history.
- Should be closely supervised by a doctor, especially in the case of women who are breast-feeding Planning to have children Or during pregnancy Especially during the last 3 months as it may affect birth and babies
- Do not take this medicine on days or times when drinking alcohol. Because it will cause bleeding in the digestive system
- This drug should not be taken for more than 10 days. NSAIDs are short-term medications. If used continuously for too long, may cause side effects from subsequent medication.
- Do not use more than the prescribed dosage. And this drug should not be used in patients with gastrointestinal disorders such as Gastroesophageal reflux, gastric or intestinal bleeding, heart disease, high blood pressure, liver disease, kidney disease, or people who use diuretics. Because the drug will increase the risk of that disease
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